SERPINB3/B4 contributes to early inflammation and barrier dysfunction in an experimental murine model of atopic dermatitis

Serine proteases are critical for epidermal barrier homeostasis and their aberrant expression and/or activity is associated with chronic skin diseases. Elevated levels of the serine protease inhibitors SERPINB3 and SERPINB4 are seen in patients with atopic dermatitis and psoriasis. However their mec...

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Dades bibliogràfiques
Publicat a:J Invest Dermatol
Autors principals: Sivaprasad, Umasundari, Kinker, Kayla G., Ericksen, Mark B., Lindsey, Mark, Gibson, Aaron M., Bass, Stacey A., Hershey, Nicolas S., Deng, Jingyuan, Medvedovic, Mario, Khurana Hershey, Gurjit K.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268075/
https://ncbi.nlm.nih.gov/pubmed/25111616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2014.353
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