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Exacerbation of allergen-induced eczema in TLR4 and TRIF deficient mice is mediated by TRIF

Despite its presence on resident skin cells, the role of TLR4 in skin diseases remains poorly understood. This is highly significant since the skin biome is rich with potential TLR4 agonists. We aimed to establish the contribution of TLR4 to atopic dermatitis and determine the mechanism by which TLR...

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Autors principals: Brandt, Eric B., Gibson, Aaron M., Bass, Stacey, Rydyznski, Carolyn, Khurana Hershey, Gurjit K.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3788607/
https://ncbi.nlm.nih.gov/pubmed/23997219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300789
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