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A computational workflow for the expansion of heterologous biosynthetic pathways to natural product derivatives

Plant natural products (PNPs) and their derivatives are important but underexplored sources of pharmaceutical molecules. To access this untapped potential, the reconstitution of heterologous PNP biosynthesis pathways in engineered microbes provides a valuable starting point to explore and produce no...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Hafner, Jasmin, Payne, James, MohammadiPeyhani, Homa, Hatzimanikatis, Vassily, Smolke, Christina
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7979880/
https://ncbi.nlm.nih.gov/pubmed/33741955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22022-5
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