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A computational workflow for the expansion of heterologous biosynthetic pathways to natural product derivatives

Plant natural products (PNPs) and their derivatives are important but underexplored sources of pharmaceutical molecules. To access this untapped potential, the reconstitution of heterologous PNP biosynthesis pathways in engineered microbes provides a valuable starting point to explore and produce no...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Hafner, Jasmin, Payne, James, MohammadiPeyhani, Homa, Hatzimanikatis, Vassily, Smolke, Christina
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7979880/
https://ncbi.nlm.nih.gov/pubmed/33741955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22022-5
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