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A computational workflow for the expansion of heterologous biosynthetic pathways to natural product derivatives

Plant natural products (PNPs) and their derivatives are important but underexplored sources of pharmaceutical molecules. To access this untapped potential, the reconstitution of heterologous PNP biosynthesis pathways in engineered microbes provides a valuable starting point to explore and produce no...

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Dades bibliogràfiques
Publicat a:Nat Commun
Autors principals: Hafner, Jasmin, Payne, James, MohammadiPeyhani, Homa, Hatzimanikatis, Vassily, Smolke, Christina
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7979880/
https://ncbi.nlm.nih.gov/pubmed/33741955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22022-5
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