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A computational workflow for the expansion of heterologous biosynthetic pathways to natural product derivatives

Plant natural products (PNPs) and their derivatives are important but underexplored sources of pharmaceutical molecules. To access this untapped potential, the reconstitution of heterologous PNP biosynthesis pathways in engineered microbes provides a valuable starting point to explore and produce no...

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Bibliografische gegevens
Gepubliceerd in:Nat Commun
Hoofdauteurs: Hafner, Jasmin, Payne, James, MohammadiPeyhani, Homa, Hatzimanikatis, Vassily, Smolke, Christina
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7979880/
https://ncbi.nlm.nih.gov/pubmed/33741955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22022-5
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