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(13)C and (15)N chemical shift assignments of A117V and M129V human Y145Stop prion protein amyloid fibrils
The C-terminally truncated Y145Stop variant of prion protein (PrP23-144) has been linked to a heritable prionopathy in humans and is also capable of triggering a transmissible prion disease in mice. PrP23-144 can be converted from soluble monomeric form to amyloid under physiological conditions, pro...
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| Pubblicato in: | Biomol NMR Assign |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7979434/ https://ncbi.nlm.nih.gov/pubmed/33123960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12104-020-09981-4 |
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