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A virtuous cycle operated by ERp44 and ERGIC-53 guarantees proteostasis in the early secretory compartment
The composition of the secretome depends on the combined action of cargo receptors that facilitate protein transport and sequential checkpoints that restrict it to native conformers. Acting after endoplasmic reticulum (ER)-resident chaperones, ERp44 retrieves its clients from downstream compartments...
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| Publicado no: | iScience |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7973864/ https://ncbi.nlm.nih.gov/pubmed/33763635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102244 |
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