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Single-cell RNA sequencing of murine islets shows high cellular complexity at all stages of autoimmune diabetes

Tissue-specific autoimmune diseases are driven by activation of diverse immune cells in the target organs. However, the molecular signatures of immune cell populations over time in an autoimmune process remain poorly defined. Using single-cell RNA sequencing, we performed an unbiased examination of...

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Detalles Bibliográficos
Publicado en:J Exp Med
Main Authors: Zakharov, Pavel N., Hu, Hao, Wan, Xiaoxiao, Unanue, Emil R.
Formato: Artigo
Idioma:Inglês
Publicado: Rockefeller University Press 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7971127/
https://ncbi.nlm.nih.gov/pubmed/32251514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20192362
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