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Resident macrophages of pancreatic islets have a seminal role in the initiation of autoimmune diabetes of NOD mice
Treatment of C57BL/6 or NOD mice with a monoclonal antibody to the CSF-1 receptor resulted in depletion of the resident macrophages of pancreatic islets of Langerhans that lasted for several weeks. Depletion of macrophages in C57BL/6 mice did not affect multiple parameters of islet function, includi...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5715775/ https://ncbi.nlm.nih.gov/pubmed/29133420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1713543114 |
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