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Macrophages and dendritic cells in islets of Langerhans in diabetic autoimmunity: a lesson on cell interactions in a mini-organ

Islets of Langerhans of all species harbor a small number of resident macrophages. These macrophages are found since birth, do not exchange with blood monocytes, and are maintained by a low level of replication. Under steady state conditions, the islet macrophages are in an activated state. Islet ma...

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Detalhes bibliográficos
Publicado no:Curr Opin Immunol
Main Authors: Carrero, Javier A., Ferris, Stephen T., Unanue, Emil. R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125905/
https://ncbi.nlm.nih.gov/pubmed/27710840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2016.09.004
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