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A minor subset of Batf3-dependent antigen presenting cells in islets of Langerhans is essential for the development of autoimmune diabetes

Autoimmune diabetes is characterized by inflammatory infiltration; however the initiating events are poorly understood. We found that the islets of Langerhans in young non-obese diabetic (NOD) mice contained two antigen presenting cell (APC) populations: a major macrophage and a minor CD103+ dendrit...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Ferris, Stephen T., Carrero, Javier A., Mohan, James F., Calderon, Boris, Murphy, Kenneth M., Unanue, Emil R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220295/
https://ncbi.nlm.nih.gov/pubmed/25367577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.09.012
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