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The MHCII peptidome of the pancreatic islet identifies key features of autoimmune peptides

The nature of autoantigens that trigger autoimmune diseases has been much discussed, but direct biochemical identification is lacking for most. Addressing this question demands unbiased examination of the self-peptides displayed by a defined autoimmune major histocompatibility complex class II (MHCI...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Immunol
Egile Nagusiak: Wan, Xiaoxiao, Vomund, Anthony N., Peterson, Orion J., Chervonsky, Alexander V., Lichti, Cheryl F., Unanue, Emil R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7117798/
https://ncbi.nlm.nih.gov/pubmed/32152506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-020-0623-7
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