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The MHCII peptidome of the pancreatic islet identifies key features of autoimmune peptides

The nature of autoantigens that trigger autoimmune diseases has been much discussed, but direct biochemical identification is lacking for most. Addressing this question demands unbiased examination of the self-peptides displayed by a defined autoimmune major histocompatibility complex class II (MHCI...

詳細記述

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書誌詳細
出版年:Nat Immunol
主要な著者: Wan, Xiaoxiao, Vomund, Anthony N., Peterson, Orion J., Chervonsky, Alexander V., Lichti, Cheryl F., Unanue, Emil R.
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7117798/
https://ncbi.nlm.nih.gov/pubmed/32152506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-020-0623-7
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