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The MHCII peptidome of the pancreatic islet identifies key features of autoimmune peptides

The nature of autoantigens that trigger autoimmune diseases has been much discussed, but direct biochemical identification is lacking for most. Addressing this question demands unbiased examination of the self-peptides displayed by a defined autoimmune major histocompatibility complex class II (MHCI...

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Bibliografiske detaljer
Udgivet i:Nat Immunol
Main Authors: Wan, Xiaoxiao, Vomund, Anthony N., Peterson, Orion J., Chervonsky, Alexander V., Lichti, Cheryl F., Unanue, Emil R.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7117798/
https://ncbi.nlm.nih.gov/pubmed/32152506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-020-0623-7
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