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Single-cell RNA sequencing of murine islets shows high cellular complexity at all stages of autoimmune diabetes

Tissue-specific autoimmune diseases are driven by activation of diverse immune cells in the target organs. However, the molecular signatures of immune cell populations over time in an autoimmune process remain poorly defined. Using single-cell RNA sequencing, we performed an unbiased examination of...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Zakharov, Pavel N., Hu, Hao, Wan, Xiaoxiao, Unanue, Emil R.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7971127/
https://ncbi.nlm.nih.gov/pubmed/32251514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20192362
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