In vitro and in vivo inhibition of malaria parasite infection by monoclonal antibodies against Plasmodium falciparum circumsporozoite protein (CSP)

Plasmodium falciparum malaria contributes to a significant global disease burden. Circumsporozoite protein (CSP), the most abundant sporozoite stage antigen, is a prime vaccine candidate. Inhibitory monoclonal antibodies (mAbs) against CSP map to either a short junctional sequence or the central (NP...

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發表在:Sci Rep
Main Authors: Livingstone, Merricka C., Bitzer, Alexis A., Giri, Alish, Luo, Kun, Sankhala, Rajeshwer S., Choe, Misook, Zou, Xiaoyan, Dennison, S. Moses, Li, Yuanzhang, Washington, William, Ngauy, Viseth, Tomaras, Georgia D., Joyce, M. Gordon, Batchelor, Adrian H., Dutta, Sheetij
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2021
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7970865/
https://ncbi.nlm.nih.gov/pubmed/33674699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-84622-x
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