Enhanced Immunity to Plasmodium falciparum Circumsporozoite Protein (PfCSP) by Using Salmonella enterica Serovar Typhi Expressing PfCSP and a PfCSP-Encoding DNA Vaccine in a Heterologous Prime-Boost Strategy

Two Salmonella enterica serovar Typhi strains that express and export a truncated version of Plasmodium falciparum circumsporozoite surface protein (tCSP) fused to Salmonella serovar Typhi cytolysin A (ClyA) were constructed as a first step in the development of a preerythrocytic malaria vaccine. Sy...

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Detalhes bibliográficos
Main Authors: Chinchilla, Magaly, Pasetti, Marcela F., Medina-Moreno, Sandra, Wang, Jin Yuan, Gomez-Duarte, Oscar G., Stout, Rick, Levine, Myron M., Galen, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951980/
https://ncbi.nlm.nih.gov/pubmed/17502396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00356-07
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