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A New Generation of Stable, Nonantibiotic, Low-Copy-Number Plasmids Improves Immune Responses to Foreign Antigens in Salmonella enterica Serovar Typhi Live Vectors
We hypothesized that adequately engineered attenuated Salmonella enterica serovar Typhi strains can serve as multivalent mucosal live vector vaccines to immunize against unrelated human pathogens. Toward this ultimate goal, we have developed a novel genetic stabilization system for antigen-expressin...
Gorde:
Egile Nagusiak: | , , , , , , , , |
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Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
American Society for Microbiology (ASM)
2010
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2798174/ https://ncbi.nlm.nih.gov/pubmed/19884333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00916-09 |
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