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A New Generation of Stable, Nonantibiotic, Low-Copy-Number Plasmids Improves Immune Responses to Foreign Antigens in Salmonella enterica Serovar Typhi Live Vectors

We hypothesized that adequately engineered attenuated Salmonella enterica serovar Typhi strains can serve as multivalent mucosal live vector vaccines to immunize against unrelated human pathogens. Toward this ultimate goal, we have developed a novel genetic stabilization system for antigen-expressin...

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Xehetasun bibliografikoak
Egile Nagusiak: Galen, James E., Wang, Jin Yuan, Chinchilla, Magaly, Vindurampulle, Christopher, Vogel, Jeffrey E., Levy, Haim, Blackwelder, William C., Pasetti, Marcela F., Levine, Myron M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798174/
https://ncbi.nlm.nih.gov/pubmed/19884333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00916-09
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