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Antibodies to Plasmodium circumsporozoite protein (CSP) inhibit sporozoite’s cell traversal activity

Plasmodium sporozoites are deposited in the skin of the mammalian host by Anopheles mosquitoes. To continue the life cycle, the sporozoites have to invade the host’s hepatocytes, where they transform into exoerythrocytic forms (EEFs) inside a parasitophorous vacuole. During their route from the skin...

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Bibliographic Details
Main Authors: Mishra, Satish, Nussenzweig, Ruth S., Nussenzweig, Victor
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310221/
https://ncbi.nlm.nih.gov/pubmed/22306356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2012.01.009
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