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Antibodies to Plasmodium circumsporozoite protein (CSP) inhibit sporozoite’s cell traversal activity

Plasmodium sporozoites are deposited in the skin of the mammalian host by Anopheles mosquitoes. To continue the life cycle, the sporozoites have to invade the host’s hepatocytes, where they transform into exoerythrocytic forms (EEFs) inside a parasitophorous vacuole. During their route from the skin...

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Detalhes bibliográficos
Main Authors: Mishra, Satish, Nussenzweig, Ruth S., Nussenzweig, Victor
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310221/
https://ncbi.nlm.nih.gov/pubmed/22306356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2012.01.009
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