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Modulation of Liver Inflammation and Fibrosis by Interleukin-37
Background and Aims: Chronic inflammation induces liver fibrosis, cirrhosis and potentially liver cancer. Kupffer cells modulate hepatic stellate cells by secreting immunologically active proteins as TGF-β. TGF-β promotes liver fibrosis via the activation of Sma- and Mad-related protein 3. IL-37 bro...
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| Veröffentlicht in: | Front Immunol |
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| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7970756/ https://ncbi.nlm.nih.gov/pubmed/33746950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.603649 |
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