Interleukin-37 Inhibits Colon Carcinogensis During Chronic Colitis

Inflammatory bowel disease increases the risk of developing colon cancer. Interleukin (IL-) 37 is a fundamental inhibitor of innate immunity by reducing systemic and local inflammation. IL-37 protein is expressed in healthy and diseased bowel and liver tissue. Here, we tested whether transgenic expr...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Mountford, Steffeni, Ringleb, Andrea, Schwaiger, Rahel, Mayr, Doris, Kobold, Sebastian, Dinarello, Charles A., Bufler, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6857648/
https://ncbi.nlm.nih.gov/pubmed/31781119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02632
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