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Suppression of Innate Inflammation and Immunity by Interleukin Family Member Interleukin-37

IL-37 is unique in the IL-1 family in that unlike other members of the family, IL-37 broadly suppresses innate immunity. IL-37 can be elevated in humans with inflammatory and autoimmune diseases where it likely functions to limit inflammation. Transgenic mice expressing human IL-37 (IL37-tg) exhibit...

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Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: Dinarello, Charles A., Nold-Petry, Claudia, Nold, Marcel, Fujita, Mayumi, Li, Suzhao, Kim, Soohyun, Bufler, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003108/
https://ncbi.nlm.nih.gov/pubmed/27060871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201545828
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