Modulation of Liver Inflammation and Fibrosis by Interleukin-37

Background and Aims: Chronic inflammation induces liver fibrosis, cirrhosis and potentially liver cancer. Kupffer cells modulate hepatic stellate cells by secreting immunologically active proteins as TGF-β. TGF-β promotes liver fibrosis via the activation of Sma- and Mad-related protein 3. IL-37 bro...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Mountford, Steffeni, Effenberger, Maria, Noll-Puchta, Heidi, Griessmair, Lucas, Ringleb, Andrea, Haas, Sonja, Denk, Gerald, Reiter, Florian P., Mayr, Doris, Dinarello, Charles A., Tilg, Herbert, Bufler, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7970756/
https://ncbi.nlm.nih.gov/pubmed/33746950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.603649
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