Cleavage and Polyadenylation Specific Factor 1 Promotes Tumor Progression via Alternative Polyadenylation and Splicing in Hepatocellular Carcinoma

Alternative polyadenylation (APA) is an important post-transcriptional regulatory mechanism required for cleavage and polyadenylation (CPA) of the 3′ untranslated region (3′ UTR) of mRNAs. Several aberrant APA events have been reported in hepatocellular carcinoma (HCC). However, the regulatory mecha...

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Vydáno v:Front Cell Dev Biol
Hlavní autoři: Chen, Shi-lu, Zhu, Zhong-xu, Yang, Xia, Liu, Li-li, He, Yang-fan, Yang, Ming-ming, Guan, Xin-yuan, Wang, Xin, Yun, Jing-ping
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Cell and Developmental Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7969726/
https://ncbi.nlm.nih.gov/pubmed/33748106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.616835
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