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Transcriptional activity regulates alternative cleavage and polyadenylation
Genes containing multiple pre-mRNA cleavage and polyadenylation sites, or polyA sites, express mRNA isoforms with variable 3′ untranslated regions (UTRs). By systematic analysis of human and mouse transcriptomes, we found that short 3′UTR isoforms are relatively more abundant when genes are highly e...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3202805/ https://ncbi.nlm.nih.gov/pubmed/21952137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2011.69 |
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