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Analysis of alterative cleavage and polyadenylation by 3′ region extraction and deep sequencing
Alternative cleavage and polyadenylation (APA) leads to mRNA isoforms with different coding sequences (CDS) and/or 3′ untranslated regions (3′UTRs). Using 3′ Region Extraction And Deep Sequencing (3′READS), a method which addresses the internal priming and oligo(A) tail issues that commonly plague p...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3560312/ https://ncbi.nlm.nih.gov/pubmed/23241633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2288 |
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