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Alternative cleavage and polyadenylation: the long and short of it

Cleavage and polyadenylation (C/P) of nascent transcripts is essential for maturation of the 3′ ends of most eukaryotic mRNAs. Over the past three decades, biochemical studies have elucidated the machinery responsible for the seemingly simple C/P reaction. Recent genomic analyses have indicated that...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tian, Bin, Manley, James L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3800139/
https://ncbi.nlm.nih.gov/pubmed/23632313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2013.03.005
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