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Alternative polyadenylation of mRNA precursors

Alternative polyadenylation (APA) is an RNA-processing mechanism that generates distinct 3′ termini on mRNAs and other RNA polymerase II transcripts. It is widespread across all eukaryotic species and is recognized as a major mechanism of gene regulation. APA exhibits tissue specificity and is impor...

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Detalhes bibliográficos
Publicado no:Nat Rev Mol Cell Biol
Main Authors: Tian, Bin, Manley, James L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5483950/
https://ncbi.nlm.nih.gov/pubmed/27677860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm.2016.116
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