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The mRNA export receptor NXF1 coordinates transcriptional dynamics, alternative polyadenylation and mRNA export
Alternative polyadenylation (APA) produces mRNA isoforms with different 3’UTR lengths. Previous studies indicated that 3’ end processing and mRNA export are intertwined in gene regulation. Here, we show that mRNA export factors generally facilitate usage of distal cleavage and polyadenylation sites...
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| Publicado no: | Mol Cell |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6450743/ https://ncbi.nlm.nih.gov/pubmed/30819645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.01.026 |
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