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The mRNA export receptor NXF1 coordinates transcriptional dynamics, alternative polyadenylation and mRNA export
Alternative polyadenylation (APA) produces mRNA isoforms with different 3’UTR lengths. Previous studies indicated that 3’ end processing and mRNA export are intertwined in gene regulation. Here, we show that mRNA export factors generally facilitate usage of distal cleavage and polyadenylation sites...
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| Pubblicato in: | Mol Cell |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6450743/ https://ncbi.nlm.nih.gov/pubmed/30819645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.01.026 |
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