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Transcriptional activators enhance polyadenylation of mRNA precursors

3′ processing of mRNA precursors is frequently coupled to transcription by RNA polymerase II (RNAP II). This coupling is well known to involve the C-terminal domain of the RNAP II largest subunit, but a variety of other transcription-associated factors have also been suggested to mediate coupling. O...

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Bibliographic Details
Main Authors: Nagaike, Takashi, Manley, James L
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256420/
https://ncbi.nlm.nih.gov/pubmed/21941122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.8.6.17210
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