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Cleavage and Polyadenylation Specific Factor 1 Promotes Tumor Progression via Alternative Polyadenylation and Splicing in Hepatocellular Carcinoma

Alternative polyadenylation (APA) is an important post-transcriptional regulatory mechanism required for cleavage and polyadenylation (CPA) of the 3′ untranslated region (3′ UTR) of mRNAs. Several aberrant APA events have been reported in hepatocellular carcinoma (HCC). However, the regulatory mecha...

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Bibliographische Detailangaben
Veröffentlicht in:Front Cell Dev Biol
Hauptverfasser: Chen, Shi-lu, Zhu, Zhong-xu, Yang, Xia, Liu, Li-li, He, Yang-fan, Yang, Ming-ming, Guan, Xin-yuan, Wang, Xin, Yun, Jing-ping
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7969726/
https://ncbi.nlm.nih.gov/pubmed/33748106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.616835
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