Cleavage and Polyadenylation Specific Factor 1 Promotes Tumor Progression via Alternative Polyadenylation and Splicing in Hepatocellular Carcinoma

Alternative polyadenylation (APA) is an important post-transcriptional regulatory mechanism required for cleavage and polyadenylation (CPA) of the 3′ untranslated region (3′ UTR) of mRNAs. Several aberrant APA events have been reported in hepatocellular carcinoma (HCC). However, the regulatory mecha...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Chen, Shi-lu, Zhu, Zhong-xu, Yang, Xia, Liu, Li-li, He, Yang-fan, Yang, Ming-ming, Guan, Xin-yuan, Wang, Xin, Yun, Jing-ping
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7969726/
https://ncbi.nlm.nih.gov/pubmed/33748106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.616835
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