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N (6)-Methyladenosines in mRNAs reduce the accuracy of codon reading by transfer RNAs and peptide release factors
We used quench flow to study how N(6)-methylated adenosines (m(6)A) affect the accuracy ratio between k(cat)/K(m) (i.e. association rate constant (k(a)) times probability (P(p)) of product formation after enzyme-substrate complex formation) for cognate and near-cognate substrate for mRNA reading by...
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| Publicado no: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7969026/ https://ncbi.nlm.nih.gov/pubmed/33561188 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab033 |
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