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Accuracy of initial codon selection by aminoacyl-tRNAs on the mRNA-programmed bacterial ribosome

We used a cell-free system with pure Escherichia coli components to study initial codon selection of aminoacyl-tRNAs in ternary complex with elongation factor Tu and GTP on messenger RNA-programmed ribosomes. We took advantage of the universal rate-accuracy trade-off for all enzymatic selections to...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Zhang, Jingji, Ieong, Ka-Weng, Johansson, Magnus, Ehrenberg, Måns
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534242/
https://ncbi.nlm.nih.gov/pubmed/26195797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1506823112
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