Cytoneme delivery of Sonic Hedgehog from ligand-producing cells requires Myosin 10 and a Dispatched-BOC/CDON co-receptor complex

Morphogens function in concentration-dependent manners to instruct cell fate during tissue patterning. The cytoneme morphogen transport model posits that specialized filopodia extend between morphogen-sending and responding cells to ensure that appropriate signaling thresholds are achieved. How morp...

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Veröffentlicht in:eLife
Hauptverfasser: Hall, Eric T, Dillard, Miriam E, Stewart, Daniel P, Zhang, Yan, Wagner, Ben, Levine, Rachel M, Pruett-Miller, Shondra M, Sykes, April, Temirov, Jamshid, Cheney, Richard E, Mori, Motomi, Robinson, Camenzind G, Ogden, Stacey K
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2021
Schlagworte:
Cell Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7968926/
https://ncbi.nlm.nih.gov/pubmed/33570491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.61432
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