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Distinct structural requirements for CDON and BOC in the promotion of Hedgehog signaling

Proper levels of Hedgehog (HH) signaling are essential during embryonic development and adult tissue homeostasis. A central mechanism to control HH pathway activity is through the regulation of secreted HH ligands at the plasma membrane. Recent studies have revealed a collective requirement for the...

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Detalhes bibliográficos
Publicado no:Dev Biol
Main Authors: Song, Jane Y., Holtz, Alexander M., Pinskey, Justine M., Allen, Benjamin L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450140/
https://ncbi.nlm.nih.gov/pubmed/25848697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2015.03.015
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