Cholesterol and CDON Regulate Sonic Hedgehog Release from Pancreatic Cancer Cells

Background: Sonic Hedgehog (Shh) is a tightly regulated membrane-associated morphogen and a known driver of tumorigenesis in pancreatic ductal adenocarcinoma (PDAC). After processing, Shh remains at the plasma membrane of Shh producing cells, thereby limiting its distribution and signal strength. In...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Pancreat Cancer
Main Authors: Alexander, Jennifer I., Martinez, Esteban, Vargas, Alberto, Zinshteyn, Daniel, Sodi, Valerie, Connolly, Denise C., Hartman, Tiffiney R., O'Reilly, Alana M.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2021
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8252898/
https://ncbi.nlm.nih.gov/pubmed/34235374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/pancan.2021.0002
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados