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Cleavage activates Dispatched for Sonic Hedgehog ligand release
Hedgehog ligands activate an evolutionarily conserved signaling pathway that provides instructional cues during tissue morphogenesis, and when corrupted, contributes to developmental disorders and cancer. The transmembrane protein Dispatched is an essential component of the machinery that deploys He...
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| Udgivet i: | eLife |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
eLife Sciences Publications, Ltd
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5811216/ https://ncbi.nlm.nih.gov/pubmed/29359685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.31678 |
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