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Dispatching Sonic Hedgehog: Molecular Mechanisms Controlling Deployment

The Hedgehog (Hh) family of morphogens direct cell fate decisions during embryogenesis and signal to maintain tissue homeostasis after birth. Hh ligands harbor dual lipid modifications that anchor the proteins into producing cell membranes, effectively preventing ligand release. The transporter-like...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Trends Cell Biol
Main Authors: Hall, Eric T., Cleverdon, Elizabeth R., Ogden, Stacey K.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6465139/
https://ncbi.nlm.nih.gov/pubmed/30852081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2019.02.005
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