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ATF3 drives senescence by reconstructing accessible chromatin profiles

Chromatin organization and transcriptional profiles undergo tremendous reordering during senescence. However, uncovering the regulatory mechanisms between chromatin reconstruction and gene expression in senescence has been elusive. Here, we depicted the landscapes of both chromatin accessibility and...

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Bibliographische Detailangaben
Veröffentlicht in:Aging Cell
Hauptverfasser: Zhang, Chao, Zhang, Xuebin, Huang, Li, Guan, Yiting, Huang, Xiaoke, Tian, Xiao‐Li, Zhang, Lijun, Tao, Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7963335/
https://ncbi.nlm.nih.gov/pubmed/33539668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13315
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