Histone Lactylation Antagonizes Senescence and Skeletal Muscle Aging by Modulating Aging‐Related Pathways

Abstract Epigenetic alterations are among the prominent drivers of cellular senescence and/or aging, intricately orchestrating gene expression programs during these processes. This study shows that histone lactylation, plays a pivotal role in counteracting senescence and mitigating dysfunctions of s...

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Hlavní autoři:	Fanju Meng, Jianuo He, Xuebin Zhang, Wencong Lyu, Ran Wei, Shiyi Wang, Zhehao Du, Haochen Wang, Jinlong Bi, Xueyang Hua, Chao Zhang, Yiting Guan, Guoliang Lyu, Xiao‐Li Tian, Lijun Zhang, Wenbing Xie, Wei Tao
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2025-06-01
Edice:	Advanced Science
Témata:	epigenetics histone lactylation senescence skeletal muscle aging
On-line přístup:	https://doi.org/10.1002/advs.202412747
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