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ATF3 drives senescence by reconstructing accessible chromatin profiles

Chromatin organization and transcriptional profiles undergo tremendous reordering during senescence. However, uncovering the regulatory mechanisms between chromatin reconstruction and gene expression in senescence has been elusive. Here, we depicted the landscapes of both chromatin accessibility and...

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Publicado en:Aging Cell
Autores principales: Zhang, Chao, Zhang, Xuebin, Huang, Li, Guan, Yiting, Huang, Xiaoke, Tian, Xiao‐Li, Zhang, Lijun, Tao, Wei
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7963335/
https://ncbi.nlm.nih.gov/pubmed/33539668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13315
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