Senescence-activated enhancer landscape orchestrates the senescence-associated secretory phenotype in murine fibroblasts

The three-dimensional configuration of the chromatin architecture is known to be crucial for alterations in the transcriptional network; however, the underlying mechanisms of epigenetic control of senescence-related gene expression by modulating the chromatin architecture remain unknown. Here, we de...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Guan, Yiting, Zhang, Chao, Lyu, Guoliang, Huang, Xiaoke, Zhang, Xuebin, Zhuang, Tenghan, Jia, Lumeng, Zhang, Lijun, Zhang, Chen, Li, Cheng, Tao, Wei
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Gene regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7641768/
https://ncbi.nlm.nih.gov/pubmed/33045748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa858
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