Cryptotanshinone Ameliorates Doxorubicin-Induced Cardiotoxicity by Targeting Akt-GSK-3β-mPTP Pathway In Vitro

Cardiotoxicity is one of the main side effects of doxorubicin (Dox) treatment. Dox could induce oxidative stress, leading to an opening of the mitochondrial permeability transition pore (mPTP) and apoptosis in cardiomyocytes. Previous studies have shown that Cryptotanshinone (Cts) has potential card...

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Publicat a:Molecules
Autors principals: Wang, Xiaoping, Sun, Qianbin, Jiang, Qianqian, Jiang, Yanyan, Zhang, Yawen, Cao, Jing, Lu, Linghui, Li, Chun, Wei, Peng, Wang, Qiyan, Wang, Yong
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7962658/
https://ncbi.nlm.nih.gov/pubmed/33800264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26051460
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