Cryptotanshinone Ameliorates Doxorubicin-Induced Cardiotoxicity by Targeting Akt-GSK-3β-mPTP Pathway In Vitro

Cardiotoxicity is one of the main side effects of doxorubicin (Dox) treatment. Dox could induce oxidative stress, leading to an opening of the mitochondrial permeability transition pore (mPTP) and apoptosis in cardiomyocytes. Previous studies have shown that Cryptotanshinone (Cts) has potential card...

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Bibliografiset tiedot
Julkaisussa:Molecules
Päätekijät: Wang, Xiaoping, Sun, Qianbin, Jiang, Qianqian, Jiang, Yanyan, Zhang, Yawen, Cao, Jing, Lu, Linghui, Li, Chun, Wei, Peng, Wang, Qiyan, Wang, Yong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2021
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7962658/
https://ncbi.nlm.nih.gov/pubmed/33800264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26051460
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