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Adiponectin Ameliorates Doxorubicin-induced Cardiotoxicity through Akt Protein-dependent Mechanism

Accumulating evidence shows that obesity is associated with doxorubicin cardiac toxicity in the heart, but the molecular mechanisms that contribute to this pathological response are not understood. Adiponectin is an adipose-derived, cardioprotective factor that is down-regulated in obesity. Here, we...

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Hlavní autoři: Maruyama, Sonomi, Shibata, Rei, Ohashi, Koji, Ohashi, Taiki, Daida, Hiroyuki, Walsh, Kenneth, Murohara, Toyoaki, Ouchi, Noriyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173230/
https://ncbi.nlm.nih.gov/pubmed/21784858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.245985
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