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Adiponectin Ameliorates Doxorubicin-induced Cardiotoxicity through Akt Protein-dependent Mechanism

Accumulating evidence shows that obesity is associated with doxorubicin cardiac toxicity in the heart, but the molecular mechanisms that contribute to this pathological response are not understood. Adiponectin is an adipose-derived, cardioprotective factor that is down-regulated in obesity. Here, we...

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Detalhes bibliográficos
Main Authors: Maruyama, Sonomi, Shibata, Rei, Ohashi, Koji, Ohashi, Taiki, Daida, Hiroyuki, Walsh, Kenneth, Murohara, Toyoaki, Ouchi, Noriyuki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173230/
https://ncbi.nlm.nih.gov/pubmed/21784858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.245985
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