Adiponectin Ameliorates Doxorubicin-induced Cardiotoxicity through Akt Protein-dependent Mechanism

Accumulating evidence shows that obesity is associated with doxorubicin cardiac toxicity in the heart, but the molecular mechanisms that contribute to this pathological response are not understood. Adiponectin is an adipose-derived, cardioprotective factor that is down-regulated in obesity. Here, we...

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Autors principals: Maruyama, Sonomi, Shibata, Rei, Ohashi, Koji, Ohashi, Taiki, Daida, Hiroyuki, Walsh, Kenneth, Murohara, Toyoaki, Ouchi, Noriyuki
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
Matèries:
Signal Transduction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173230/
https://ncbi.nlm.nih.gov/pubmed/21784858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.245985
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