Adiponectin deficiency exacerbates cardiac dysfunction following pressure overload through disruption of an AMPK-dependent angiogenic response

BACKGROUND: Although increasing evidence indicates that an adipokine adiponectin exerts protective actions on heart, its effects on coronary angiogenesis following pressure overload have not been examined previously. Because disruption of angiogenesis during heart growth leads to contractile dysfunc...

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Hauptverfasser: Shimano, Masayuki, Ouchi, Noriyuki, Shibata, Rei, Ohashi, Koji, Pimentel, David R., Murohara, Toyoaki, Walsh, Kenneth
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885542/
https://ncbi.nlm.nih.gov/pubmed/20206634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2010.02.021
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