Hsp20 Interacting with Phosphorylated Akt Reduces Doxorubicin-Triggered Oxidative Stress and Cardiotoxicity

Doxorubicin (DOX) is a widely used antitumor drug, but its application is limited due to its cardiotoxic side effects. Hsp20 has been recently shown to protect cardiomyocytes against apoptosis, induced by ischemia/reperfusion injury or by prolonged β-agonist stimulation. However, it is not clear whe...

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Hlavní autoři: Fan, Guo-Chang, Zhou, Xiaoyang, Wang, Xiaohong, Song, Guojie, Qian, Jiang, Nicolaou, Persoulla, Chen, Guoli, Ren, Xiaoping, Kranias, Evangelia G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763388/
https://ncbi.nlm.nih.gov/pubmed/18948619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.182832
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