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Blockade of Hsp20 Phosphorylation Exacerbates Cardiac Ischemia/Reperfusion Injury by Suppressed Autophagy and Increased Cell Death

RATIONALE: The levels of a small heat shock protein 20 (Hsp20) and its phosphorylation are increased upon ischemic insults, and overexpression of Hsp20 protects the heart against ischemia/reperfusion injury. However, the mechanism underlying cardioprotection of Hsp20 and especially the role of its p...

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Bibliografske podrobnosti
Main Authors: Qian, Jiang, Ren, Xiaoping, Wang, Xiaohong, Zhang, Pengyuan, Jones, W. Keith, Molkentin, Jeffery D., Fan, Guo-Chang, Kranias, Evangelia G.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799045/
https://ncbi.nlm.nih.gov/pubmed/19850943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.200378
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