Cryptotanshinone Ameliorates Doxorubicin-Induced Cardiotoxicity by Targeting Akt-GSK-3β-mPTP Pathway In Vitro

Cardiotoxicity is one of the main side effects of doxorubicin (Dox) treatment. Dox could induce oxidative stress, leading to an opening of the mitochondrial permeability transition pore (mPTP) and apoptosis in cardiomyocytes. Previous studies have shown that Cryptotanshinone (Cts) has potential card...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Wang, Xiaoping, Sun, Qianbin, Jiang, Qianqian, Jiang, Yanyan, Zhang, Yawen, Cao, Jing, Lu, Linghui, Li, Chun, Wei, Peng, Wang, Qiyan, Wang, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7962658/
https://ncbi.nlm.nih.gov/pubmed/33800264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26051460
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